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Summary Rare PGM1 variants in Macushi and Wayampi Amerindian populations have been compared electrophoretically and by means of electrofocusing. They appear to be identical. The findings are discussed. 相似文献
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Beringer JE 《Biologist (London, England)》2000,47(2):81-84
Despite strict regulation and a clean safety record, research and development of genetically modified (GM) crops and other organisms has been confronted with tremendous public hostility. Why has this happened, and how can scientists try to guide the debate into more rational channels? The answers may determine the future of GM technology and our ability to provide for a growing world population. 相似文献
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Hadley C 《American journal of physical anthropology》2005,126(4):471-480
Anthropologists and demographers have devoted considerable attention to testing the fertility-polygyny hypothesis, which posits that polygynously married women have lower fertility than their monogamously married counterparts. Much less attention has been paid to the potential impact of polygynous marriages on the health and well-being of children. The objective of this paper was to assess whether polygynous marital status is a risk factor for poor nutritional status and growth performance among a cohort of young Tanzanian children. Using data collected from both wet and dry season periods, we tested for an association from both cross-sectional and longitudinal perspectives. Despite relatively high nutritional status compared to other agropastoralists and horticultural populations, as well as the presence of various socioecological factors that were expected to mitigate any "costs" to polygynous marriage, we found that among our target population, polygynous marital status is a risk factor for poor growth performance. This association is most pronounced in the wet season, and maintains even after allowing for the potential influences of child age and sex, and household characteristics. These results counter our original expectation, and suggest that polygyny is costly to children in this population; this does not appear to be the result of difference in early child environment or household wealth. 相似文献
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This study investigated whether a putative shift in climate regime in the North Atlantic in the 1990s coincided with changes in the growth and recruitment of roach Rutilus rutilus in the north-east of England. The relationships between R. rutilus growth and recruitment and the environment were significantly different before and after the putative shift in climate regime. Water temperature, river discharge, growth, recruitment success and the Gulf Stream Index co-varied until the late 1990s, indicating a gradual progression between periods of warm-and-dry and cold-and-wet summers. Since the late 1990s, there has been an increased prevalence of warm-and-wet summers, and recruitment success has oscillated between extremes on an almost annual basis. The north wall (northern boundary) of the Gulf Stream has been undergoing a displacement south since the late 1990s, and the speed and amplitude of the change appears to support the hypothesis that there was a regime shift in the climate of the North Atlantic Ocean. It is possible that a continued displacement south of the north wall of the Gulf Stream will lead to further increases in river discharge, reductions in water temperature and reduced fish growth and recruitment success in the long term. 相似文献
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Jung H 《Radiation and environmental biophysics》2001,40(2):169-174
The risk of radiation-induced breast cancer decreases with increasing age at exposure. Thus, for calculating the individual
risk for a patient undergoing mammography, age-related risk coefficients need to be used. In this report, the results of epidemiological
studies on risks of radiation-induced breast cancer are reviewed indicating that the available data do not show the risk to
be enhanced for women exposed at the age of 55 years or older. This lack of evidence is reflected by the fact that the risk
coefficients recommended by national and international advisory bodies differ by a factor of 10 or more for age at exposure
of 50–60 years or older. A hypothesis is proposed indicating that the risk of radiation-induced breast cancer might decrease
considerably at the time of menopause. The hypothesis is based on the following line of arguments: (1) evidence has accumulated
from molecular genetic studies indicating that the development of colorectal cancer requires a cascade of subsequent mutations
consisting of at least seven genetic events. (2) For colorectal cancer, the annual rates of incidence and mortality increase
with age to the power of 5–6. Thus, the number of mutation steps (minus 1) is approximately reflected by the power of age
dependence. (3) For western populations, the incidence and mortality of breast cancer up to the age of about 50 years increase
with age to the power of about 6, indicating that a similar number of genetic events might be involved in development of breast
cancer as has been identified for colorectal cancer. (4) For women aged 50 years or older, breast cancer occurs at an annual
rate that is about proportional to age or age squared. This may mean that after menopause, the processes in the multistep
mutation cascade leading to breast cancer are slowed down by a factor of about 4 or more. (5) The constant relative risk model
of radiation carcinogenesis implies for solid cancers that radiation acts by inducing additional mutations in the earlier
steps of the multistep cascade. It is suggested that the break-point in the age-specific annual rate of breast cancer incidence
at menopause is associated with a corresponding drop in radiation sensitivity with respect to induction of breast cancer.
Received: 8 January 2001 / Accepted: 20 March 2001 相似文献
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Many species of coral reef fishes form pairs. While it is assumed that pairs represent the breeding unit of these species, the reproductive status of paired versus solitary individuals, and changes in status associated with pair-formation have seldom been investigated. In order to assess whether pairing is related to reproduction we examined whether the ontogenetic timing of pair formation coincided with the onset of maturation in four species of fishes: Chaetodon lunulatus and Chaetodon melannotus (family Chaetodontidae), and Valenciennea muralis and Valenciennea strigata (family Gobiidae). 65–78% of all fishes occurred in pairs. In C. lunulatus and V. muralis, pair-formation coincided with maturation, suggesting that these species form pairs for breeding. Further, C. lunulatus and V. muralis exhibited significant positive size-assortative pairing, which is often associated with monogamous mating. In contrast, pair formation in C. melannotus and V. strigata did not coincide with maturation. In both these species many solitary individuals were reproductive, and same sex pairs were common. While reproduction may be the basis for pairing in some species, both solitary and paired individuals are capable of breeding in others. We propose that non-reproductive mechanisms, such as predator vigilance, may explain pair-formation in coral reef fishes with non-monogamous breeding systems. 相似文献
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Rennie S 《Trends in parasitology》2004,20(4):163; author reply 164
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D V Coleman 《BMJ (Clinical research ed.)》1979,1(6169):1031-1032
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Pedro Monterroso Neftalí Sillero Luís Miguel Rosalino Filipa Loureiro Paulo Célio Alves 《Ecology and evolution》2013,3(7):2285-2295
Most studies dealing with home ranges consider the study areas as if they were totally flat, working only in two dimensions, when in reality they are irregular surfaces displayed in three dimensions. By disregarding the third dimension (i.e., topography), the size of home ranges underestimates the surface actually occupied by the animal, potentially leading to misinterpretations of the animals' ecological needs. We explored the influence of considering the third dimension in the estimation of home‐range size by modeling the variation between the planimetric and topographic estimates at several spatial scales. Our results revealed that planimetric approaches underestimate home‐range size estimations, which range from nearly zero up to 22%. The difference between planimetric and topographic estimates of home‐ranges sizes produced highly robust models using the average slope as the sole independent factor. Moreover, our models suggest that planimetric estimates in areas with an average slope of 16.3° (±0.4) or more will incur in errors ≥5%. Alternatively, the altitudinal range can be used as an indicator of the need to include topography in home‐range estimates. Our results confirmed that home‐range estimates could be significantly biased when topography is disregarded. We suggest that study areas where home‐range studies will be performed should firstly be scoped for its altitudinal range, which can serve as an indicator for the need for posterior use of average slope values to model the surface area used and/or available for the studied animals. 相似文献
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Is there a single biochemical adaptation to anhydrobiosis? 总被引:3,自引:1,他引:2
Even though water is required for the maintenance of biologicalintegrity, numerous organisms are capable of surviving lossof virtually all their cellular water and existing in a stateknown as anhydrobiosis. Over the past three decades we and othershave established that disaccharides such as trehalose and sucroseare almost certainly involved in stabilizing the dry cells.We discuss here some of the evidence behind the mechanism ofthis stabilization. Until the past few years this mechanismhas been sufficiently appealing that a consensus has been developingthat acquisition of these sugars in the cytoplasm may be bothnecessary and sufficient for anhydrobiosis. We show here thatthere are other routes to achieve the effects conferred by thesugars and that other adaptations are almost certainly required,at least in environmental conditions that are less than optimal.Under optimal storage conditions, the presence of the sugarsalone may be sufficient to stabilize even mammalian cells inthe dry state, findings that are already finding use in humanclinical medicine. 相似文献
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