Kupffer-cell-derived IL-6 is repurposed for hepatocyte dedifferentiation via activating progenitor genes from injury-specific enhancers

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Phase separation of OCT4 controls TAD reorganization to promote cell fate transitions

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CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion

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Capybara: A computational tool to measure cell identity and fate transitions

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FOXC2 promotes vasculogenic mimicry and resistance to anti-angiogenic therapy

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Greater epithelial ridge cells are the principal organoid-forming progenitors of the mouse cochlea

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The landscape of pioneer factor activity reveals the mechanisms of chromatin reprogramming and genome activation

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STAT Signaling Modifies Ascl1 Chromatin Binding and Limits Neural Regeneration from Muller Glia in Adult Mouse Retina

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Comparative transcriptomics reveals circadian and pluripotency networks as two pillars of longevity regulation

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Highly efficient and rapid generation of human pluripotent stem cells by chemical reprogramming

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Direct chemical reprogramming of human cord blood erythroblasts to induced megakaryocytes that produce platelets

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Adaptations in Hippo-Yap signaling and myofibroblast fate underlie scar-free ear appendage wound healing in spiny mice

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Transcription factor induction of vascular blood stem cell niches in vivo

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Nitrate availability controls translocation of the transcription factor NAC075 for cell-type-specific reprogramming of root growth

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Principles of signaling pathway modulation for enhancing human naive pluripotency induction

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Glioma-Derived miRNA-Containing Extracellular Vesicles Induce Angiogenesis by Reprogramming Brain Endothelial Cells

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Loss of epigenetic information as a cause of mammalian aging

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5-Azacytidine- and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-SMAD4 signaling

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Adenine base editing and prime editing of chemically derived hepatic progenitors rescue genetic liver disease

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NeuroD1 induces microglial apoptosis and cannot induce microglia-to-neuron cross-lineage reprogramming

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