Structural interactions define assembly adapter function of a type II secretion system pseudopilin

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Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis

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Sarbecovirus ORF6 proteins hamper induction of interferon signaling

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Structure and dynamic association of an assembly platform subcomplex of the bacterial type II secretion system

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Integrated regulatory network in Pseudomonas syringae reveals dynamics of virulence

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Palmitoylation couples insulin hypersecretion with β cell failure in diabetes

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Structure of the enterococcal T4SS protein PrgL reveals unique dimerization interface in the VirB8 protein family

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Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling

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Quorum-sensing- and type VI secretion-mediated spatiotemporal cell death drives genetic diversity in Vibrio cholerae

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Tracing cell-type evolution by cross-species comparison of cell atlases

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An ancestral mycobacterial effector promotes dissemination of infection

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ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer

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A rapid RIG-I signaling relay mediates efficient antiviral response

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Crosstalk between ILC2s and Th2 cells varies among mouse models

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Allosteric control of type I-A CRISPR-Cas3 complexes and establishment as effective nucleic acid detection and human genome editing tools

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Structural insights into caspase ADPR deacylization catalyzed by a bacterial effector and host calmodulin

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Cryo-EM structure of the Agrobacterium tumefaciens T-pilus reveals the importance of positive charges in the lumen

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Insulin Treatment Is Associated with Increased Mortality in Patients with COVID-19 and Type 2 Diabetes

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Transbilayer Movement of Sphingomyelin Precedes Catastrophic Breakage of Enterobacteria-Containing Vacuoles

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Target RNA activates the protease activity of Craspase to confer antiviral defense

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