Monoallelic pathogenic ALG5 variants cause atypical polycystic kidney disease and interstitial fibrosis

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Comprehensive single-cell transcriptional profiling defines shared and unique epithelial injury responses during kidney fibrosis

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A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery

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The probiotic L. casei Zhang slows the progression of acute and chronic kidney disease

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Plasticity of distal nephron epithelia from human kidney organoids enables the induction of ureteric tip and stalk

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Spatial dynamic metabolomics identifies metabolic cell fate trajectories in human kidney differentiation

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Mapping the single-cell transcriptomic response of murine diabetic kidney disease to therapies

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The developing murine kidney actively negotiates geometric packing conflicts to avoid defects

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A methionine-Mettl3-N6-methyladenosine axis promotes polycystic kidney disease

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A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells

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Erythrocyte transglutaminase-2 combats hypoxia and chronic kidney disease by promoting oxygen delivery and carnitine homeostasis

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DNA-damaged podocyte-CD8 T cell crosstalk exacerbates kidney injury by altering DNA methylation

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Uncoupled glycerol-3-phosphate shuttle in kidney cancer reveals that cytosolic GPD is essential to support lipid synthesis

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Genome-wide screening in human kidney organoids identifies developmental and disease-related aspects of nephrogenesis

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KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease

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Depletion of CUL4B in macrophages ameliorates diabetic kidney disease via miR-194-5p/ITGA9 axis

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Progressive liver,kidney, and heart degeneration in children and adults affected by TULP3 mutations

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Fungal sensing enhances neutrophil metabolic fitness by regulating antifungal Glut1 activity

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Lipocalin-2 induces mitochondrial dysfunction in renal tubular cells via mTOR pathway activation

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RNA mis-splicing drives viral mimicry response after DNMTi therapy in SETD2-mutant kidney cancer

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