Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance

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Metoclopramide treatment blocks CD93-signaling-mediated self-renewal of chronic myeloid leukemia stem cells

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Vitamin D Receptor Controls Cell Stemness in Acute Myeloid Leukemia and in Normal Bone Marrow

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Loss of PRMT7 reprograms glycine metabolism to selectively eradicate leukemia stem cells in CML

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Intrinsically disordered Meningioma-1 stabilizes the BAF complex to cause AML

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R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis

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ATP-site inhibitors induce unique conformations of the acute myeloid leukemia-associated Src-family kinase,Fgr

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Low-density-lipoprotein-receptor-related protein 1 mediates Notch pathway activation

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ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency

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GTAC enables parallel genotyping of multiple genomic loci with chromatin accessibility profiling in single cells

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The requirement for pyruvate dehydrogenase in leukemogenesis depends on cell lineage

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ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms

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A common binding motif in the ET domain of BRD3 forms polymorphic structural interfaces with host and viral proteins

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ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase

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CBFβ-SMMHC Affects Genome-wide Polycomb Repressive Complex 1 Activity in Acute Myeloid Leukemia

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MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape

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Definition of a small core transcriptional circuit regulated by AML1-ETO

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Molecular Mechanism of LEDGF/p75 Dimerization

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Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy

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A plant immune protein enables broad antitumor response by rescuing microRNA deficiency

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