Effects of parametric manipulation of inter-stimulus similarity on 3D object categorization

To explore the nature of the representation space of 3D objects, we studied human performance in forced-choice categorization of objects composed of four geon-like parts emanating from a common center. Two categories were defined by prototypical objects, distinguished by qualitative properties of their parts (bulging vs waist-like limbs). Subjects were trained to discriminate between the two prototypes (shown briefly, from a number of viewpoints, in stereo) in a 1-interval forced-choice task, until they reached a 90% correct-response performance level. After training, in the first experiment, 11 subjects were tested on shapes obtained by varying the prototypical parameters both orthogonally (ORTHO) and in parallel (PARA) to the line connecting the prototypes in the parameter space. For the eight subjects who performed above chance, the error rate increased with the ORTHO parameter-space displacement between the stimulus and the corresponding prototype; the effect of the PARA displacement was weaker. Thus, the parameter-space location of the stimuli mattered more than the qualitative contrasts, which were always present. To find out whether both prototypes or just the nearest one to the test shape influenced the decision, in the second experiment we varied the similarity between the categories. Specifically, in the test stage trials the distance between the two prototypes could assume one of three values (FAR, INTERMEDIATE, and NEAR). For the 13 subjects who performed above chance, the error rate (on physically identical stimuli) in the NEAR condition was higher than in the other two conditions. The results of the two experiments contradict the prediction of theories that postulate exclusive reliance on qualitative contrasts, and support the notion of a representation space in which distances to more than one reference point or prototype are encoded (Edelman, 1998).     

Associatieve visuele agnosie. De minder zichtbare gevolgen van een herseninfarct

After a cerebral infarction, some patients acutely demonstrate contralateral hemiplegia, or aphasia. Those are the obvious symptoms of a cerebral infarction. However, less visible but burdensome consequences may go unnoticed without closer investigation. The importance of a thorough clinical examination is exemplified by a single case study of a 72-year-old, right-handed male. Two years before he had suffered from an ischemic stroke in the territory of the left posterior cerebral artery, with right homonymous hemianopia and global alexia (i.e., impairment in letter recognition and profound impairment of reading) without agraphia. Naming was impaired on visual presentation (20%-39% correct), but improved significantly after tactile presentation (87% correct) or verbal definition (89%). Pre-semantic visual processing was normal (correct matching of different views of the same object), as was his access to structural knowledge from vision (he reliably distinguished real objects from non-objects). On a colour decision task he reliably indicated which of two items was coloured correctly. Though he was unable to mime how visually presented objects were used, he more reliably matched pictures of objects with pictures of a mime artist gesturing the use of the object. He obtained normal scores on word definition (WAIS-III), synonym judgment and word-picture matching tasks with perceptual and semantic distractors. He however failed when he had to match physically dissimilar specimens of the same object or when he had to decide which two of five objects were related associatively (Pyramids and Palm Trees Test). The patient thus showed a striking contrast in his intact ability to access knowledge of object shape or colour from vision and impaired functional and associative knowledge. As a result, he could not access a complete semantic representation, required for activating phonological representations to name visually presented objects. The pattern of impairments and preserved abilities is considered to be a specific difficulty to access a full semantic representation from an intact structural representation of visually presented objects, i.e., a form of visual object agnosia.     

Recognition of facial expressions in a Japanese monkey (Macaca fuscata) and humans (Homo sapiens)

Recognition of facial expressions by a Japanese monkey and two humans was studied. The monkey subject matched 20 photographs of monkey facial expressions and 20 photographs of human facial expressions. Humans sorted the same pictures. Matching accuracy by the monkey was about 80% correct for both human and monkey facial expressions. The confusion matrices of those facial expressions were analyzed by a multi-dimensional scaling procedure (MDSCAL). The resulting MDS plots suggested that the important cues in recognizing facial expressions of monkeys were “thrusting the mouth” and ‘raising the eyebrows.” Comparison of the MDS plots by the monkey subject with those by human subjects suggested that the monkey categorized the human “happiness” faces. This may suggest that the monkey has an ability to recognize human smile face even though it is learned. However, the monkey did not differentiate the human “anger/disgust” faces from the human “sad” faces, while human subjects clearly did. This may correlate with the lack of eyebrow movement in monkeys.     

Spontaneous behavior of a rhesus monkey (Macaca mulatta) during memory tests suggests memory awareness

Humans can predict with some accuracy whether or not they know the correct answer to a question before responding. In some cases the capacity to make such predictions depends on memory awareness, the ability to introspectively discriminate between knowing and not knowing. In this unplanned retrospective analysis of video taped behavior we asked whether a rhesus monkey's apparent frustration predicted his accuracy in a matching-to-sample task on a trial-by-trial basis. The monkey was likely to aggressively strike the computer touchscreen when committing errors, whereas he generally touched the screen more gently when selecting the correct stimulus. This difference in behavior, which occurred before the monkey received feedback on the accuracy of his choice, suggests that he knew whether or not he remembered the correct response.     

Characteristics of Human Luminance Discrimination and Modeling a Neural Network Based on the Response Properties of the Visual Cortex

Reaction time (RT) and error rate that depend on stimulus duration were measured in a luminance-discrimination reaction time task. Two patches of light with different luminance were presented to participants for ‘short’ (150 ms) or ‘long’ (1 s) period on each trial. When the stimulus duration was ‘short’, the participants responded more rapidly with poorer discrimination performance than they did in the longer duration. The results suggested that different sensory responses in the visual cortices were responsible for the dependence of response speed and accuracy on the stimulus duration during the luminance-discrimination reaction time task. It was shown that the simple winner-take-all-type neural network model receiving transient and sustained stimulus information from the primary visual cortex successfully reproduced RT distributions for correct responses and error rates. Moreover, temporal spike sequences obtained from the model network closely resembled to the neural activity in the monkey prefrontal or parietal area during other visual decision tasks such as motion discrimination and oddball detection tasks.     

Symmetry cues for matching mirrored objects

The study explores cues for matching pairs of objects. These objects were arranged into mirror-symmetrical displays and the task was to judge whether a pre-specified 180 degree rotation around the X, Y or Z axis carries one object into the mirror object. For some rotations, the object's mirror symmetry (M) and, for other rotations, the object's point-symmetry (P) could serve as a cue. The matching results suggest that M is a better cue than P, say M > P. Various attempts are made to explain this effect. The most promising one focuses on simplest structural object representations as these capture M and not P. It is furthermore plausible that M captured by reference frames at high hierarchical representation levels, say M1, serves as a better cue than M captured at low levels, say M2. The prediction M1 > M2 > P merely applies to the open surface objects in the experiment. For the closed solid objects in the experiment the expectation is M1 = M2 = P. Both predictions roughly agree with the accuracy and reaction-time data. The results suggest the perceptual relevance of representation cues and, aditionally, that cues stemming from reference frames at higher hierarchical representation levels are more effective than those from lower levels.     

Perception of successive brief objects as a function of stimulus onset asynchrony: model experiments based on two-stage synchronization of neuronal oscillators

Recently we introduced a new version of the perceptual retouch model incorporating two interactive binding operations—binding features for objects and binding the bound feature-objects with a large scale oscillatory system that acts as a mediary for the perceptual information to reach consciousness-level representation. The relative level of synchronized firing of the neurons representing the features of an object obtained after the second-stage synchronizing modulation is used as the equivalent of conscious perception of the corresponding object. Here, this model is used for simulating interaction of two successive featured objects as a function of stimulus onset asynchrony (SOA). Model output reproduces typical results of mutual masking—with shortest and longest SOAs first and second object correct perception rate is comparable while with intermediate SOAs second object dominates over the first one. Additionally, with shortest SOAs misbinding of features to form illusory objects is simulated by the model.     

Multiple classification performance of juvenile chimpanzees,normal children,and retarded children

The cognitive capacities of juvenile chimpanzees, normal children, and retarded children were evaluated by using a nonverbal, Piagetian-type multiple classification task. The three groups of subjects were tested with the same two by two stimulus matrix, which was formed by combining two different colors with two different shapes. On each problem the subjects were required to select one of four stimulus items from the response tray and place it inside the empty cell of the stimulus matrix. It was found that the human and nonhuman primates tested were able to select objects with correct color and shape cues (C⁺/S⁺)significantly more often than the other objects with only color cues correct (C⁺/S^-), only shape cues correct (C^-/S⁺), or neither cue correct (C^-/S^-). Although the two groups of human children were able to select the C⁺/S⁺ objects about 100% of the time by the end of testing, the normal children required significantly fewer problems than the retarded children. The juvenile chimpanzees needed significantly more problems than the human subjects before they consistently selected the C⁺/S⁺ object on the first trial and attained a level of correct responding that was above chance. Moreover, their level of performance did not exceed 70% correct. These data suggest that the human children (both normal and retarded) used a conceptual strategy, while the juvenile chimpanzees employed a perceptual strategy to solve the multiple classification problems. The relationship between language and conceptual problem-solving strategies for Piagetiantype tasks is discussed. Portions of the data reported in this study were presented at the Annual Meeting of the Southern Psychological Association, Atlanta, Georgia, March 15–18, 1978.     

Picture processing in tufted capuchin monkeys (Cebus apella)

Although pictures are frequently used in place of real objects to investigate various aspects of cognition in different non-human species, there is little evidence that animals treat pictorial stimuli as representations of the real objects. In the present study, we carried out four experiments designed to assess picture processing in tufted capuchin monkeys (Cebus apella), using a simultaneous Matching-to-Sample (MTS) task. The results of the first three experiments indicate that capuchins are able to match objects with their colour photographs and vice versa, and that object-picture matching in this New World monkey species is not due to picture-object confusion. The results of the fourth experiment show that capuchins are able to recognize objects in their pictures with a high level of accuracy even when less realistic images, such as black-and-white photographs, silhouettes and line drawings, are employed as bi-dimensional stimuli. Overall, these findings indicate that capuchin monkeys are able to establish a correspondence between the real objects and their pictorial representations.     

Perception of size and lightness of human observers: two criteria for holistic and analytic processing show no correlation in individuals

Results of a triad-classification task and a multidimensional-scaling (MDS) experiment are compared for individual observers. Both paradigms are designed to reveal whether stimuli are perceived in aholistic oranalytic manner (Garner 1974). Subjects differed substantially and consistently in their triad classification pattern (Figs. 3, 5): The majority of subjects selected stimuli according todimensional criteria; this classification type is thought to indicate an analytic stimulus processing. Approximately one third of subjects, however, used a classification according to overall similarity (indicating holistic processing). Except for the very first session (Fig. 3a), virtually no intermediate classifications occurred (Fig. 3b, c). This clear separation into two classification types suggests that there actually existtwo strongly preferred processing modes.Intraindividual variability between sessions in general was small (Fig. 5). In one case, however, a spontaneous switching from a purely dimensional classification to a purely similarity classification occurred (Fig. 5d). This indicates that the observers have different processing options at their disposal, and are not forced to use a particular processing mode by the stimulus type — as has been supposed in the original concept of integrality/separability of stimuli (Garner 1974). In the MDS experiment also substantial interindividual differences in the best-fitting Minkowski metric were found, indicating different processing types. However, for individuals participating in both experiments, there wasno correlation between the results of the two experimental paradigms. This is interpreted as a result of the subject's ability to choose between a few perceptual-processing options.     

Effects of Degree and Timing of Social Housing on Reversal Learning and Response to Novel Objects in Dairy Calves

Rodents and primates deprived of early social contact exhibit deficits in learning and behavioural flexibility. They often also exhibit apparent signs of elevated anxiety, although the relationship between these effects has not been studied. To investigate whether dairy calves are similarly affected, we first compared calves housed in standard individual pens (n = 7) to those housed in a dynamic group with access to their mothers (n = 8). All calves learned to approach the correct stimulus in a visual discrimination task. Only one individually housed calf was able to re-learn the task when the stimuli were reversed, compared to all but one calf from the group. A second experiment investigated whether this effect might be explained by anxiety in individually housed animals interfering with their learning, and tested varying degrees of social contact in addition to the complex group: pair housing beginning early (approximately 6 days old) and late (6 weeks old). Again, fewer individually reared calves learned the reversal task (2 of 10 or 20%) compared to early paired and grouped calves (16 of 21 or 76% of calves). Late paired calves had intermediate success. Individually housed calves were slower to touch novel objects, but the magnitude of the fear response did not correlate with reversal performance. We conclude that individually housed calves have learning deficits, but these deficits were not likely associated with increased anxiety.     

Efficient encoding of spectrotemporal information for bat echolocation

In most animals, natural stimuli are characterized by a high degree of redundancy, limiting the ensemble of ecologically valid stimuli to a significantly reduced subspace of the representation space. Neural encodings can exploit this redundancy and increase sensing efficiency by generating low-dimensional representations that retain all information essential to support behavior. In this study, we investigate whether such an efficient encoding can be found to support a broad range of echolocation tasks in bats. Starting from an ensemble of echo signals collected with a biomimetic sonar system in natural indoor and outdoor environments, we use independent component analysis to derive a low-dimensional encoding of the output of a cochlear model. We show that this compressive encoding retains all essential information. To this end, we simulate a range of psycho-acoustic experiments with bats. In these simulations, we train a set of neural networks to use the encoded echoes as input while performing the experiments. The results show that the neural networks’ performance is at least as good as that of the bats. We conclude that our results indicate that efficient encoding of echo information is feasible and, given its many advantages, very likely to be employed by bats. Previous studies have demonstrated that low-dimensional encodings allow for task resolution at a relatively high level. In contrast to previous work in this area, we show that high performance can also be achieved when low-dimensional filters are derived from a data set of realistic echo signals, not tailored to specific experimental conditions.     

Variability in 5- and 8-year-olds' memory for duration: an interfering task in temporal bisection

The purpose of this experiment was to investigate 5- and 8-year-olds' long-term memory for stimulus duration in a bisection task. Children were trained to discriminate between a short and a long standard duration presented as visual stimulus for 2 and 8 s, respectively. They had then to decide whether an intermediate stimulus duration was more similar to the short or to the long standard in two identical testing phases separated by an interfering task lasting for 15 min (immediate test vs. deferred test). The results showed that the 5- and the 8-year-olds produced orderly psychophysical functions. However, the 8-year-olds produced psychophysical functions, which increased more abruptly with the increasing stimulus duration. Nevertheless, whatever the age of children tested, the psychophysical function curves were flatter in the deferred test than in the immediate test, and more particularly in the 5-year-olds. Furthermore, the 5-year-olds produced fewer 'long' responses in the deferred than in the immediate test. Modeling of the data suggests that the variability of the representation of the standard in long-term memory was higher in the 5- than in the 8-year-olds and that the interfering task increased this memory variability.     

Acquisition of visually guided conditional associative tasks in Göttingen minipigs

Fourteen Göttingen minipigs were trained on two different visually guided conditional associative tasks. In a spatial conditional task, a black stimulus signalled that a response to the left was correct, and a white stimulus signalled that a response to the right was correct. In a conditional go/no-go task, a blue stimulus signalled go, and a red stimulus signalled no-go. The pigs were trained until a behavioural criterion of 90% correct for each of two consecutive sessions. For the spatial conditional task, all pigs reached this criterion in 520 trials or less. For the conditional go/no-go task, all pigs, except three, reached this criterion in 1600 trials or less. Sows and boars learned equally fast. The tasks can be useful for the testing of cognitive function in pig models of human brain disorders.     

Social Suppressive Behavior Is Organized by the Spatiotemporal Integration of Multiple Cortical Regions in the Japanese Macaque

Under social conflict, monkeys develop hierarchical positions through social interactions. Once the hierarchy is established, the dominant monkey dominates the space around itself and the submissive monkey tries not to violate this space. Previous studies have shown the contributions of the frontal and parietal cortices in social suppression, but the contributions of other cortical areas to suppressive functions remain elusive. We recorded neural activity in large cortical areas using electrocorticographic (ECoG) arrays while monkeys performed a social food-grab task in which a target monkey was paired with either a dominant or a submissive monkey. If the paired monkey was dominant, the target monkey avoided taking food in the shared conflict space, but not in other areas. By contrast, when the paired monkey was submissive, the target monkey took the food freely without hesitation. We applied decoding analysis to the ECoG data to see when and which cortical areas contribute to social behavioral suppression. Neural information discriminating the social condition was more evident when the conflict space was set in the area contralateral to the recording hemisphere. We found that the information increased as the social pressure increased during the task. Before food presentation, when the pressure was relatively low, the parietal and somatosensory–motor cortices showed sustained discrimination of the social condition. After food presentation, when the monkey faced greater pressure to make a decision as to whether it should take the food, the prefrontal and visual cortices started to develop buildup responses. The social representation was found in a sustained form in the parietal and somatosensory–motor regions, followed by additional buildup form in the visual and prefrontal cortices. The representation was less influenced by reward expectation. These findings suggest that social adaptation is achieved by a higher-order self-regulation process (incorporating motor preparation/execution processes) in accordance with the embodied social contexts.     

Prefrontal neurons predict choices during an auditory same-different task

The detection of stimuli is critical for an animal's survival [1]. However, it is not adaptive for an animal to respond automatically to every stimulus that is present in the environment [2-5]. Given that the prefrontal cortex (PFC) plays a key role in executive function [6-8], we hypothesized that PFC activity should be involved in context-dependent responses to uncommon stimuli. As a test of this hypothesis, monkeys participated in a same-different task, a variant of an oddball task [2]. During this task, a monkey heard multiple presentations of a "reference" stimulus that were followed by a "test" stimulus and reported whether these stimuli were the same or different. While they participated in this task, we recorded from neurons in the ventrolateral prefrontal cortex (vPFC; a cortical area involved in aspects of nonspatial auditory processing [9, 10]). We found that vPFC activity was correlated with the monkeys' choices. This finding demonstrates a direct link between single neurons and behavioral choices in the PFC on a nonspatial auditory task.     

Transfer of a Serial Representation between Two Distinct Tasks by Rhesus Macaques

Do animals form task-specific representations, or do those representations take a general form that can be applied to qualitatively different tasks? Rhesus monkeys (Macaca mulatta) learned the ordering of stimulus lists using two different serial tasks, in order to test whether prior experience in each task could be transfered to the other, enhancing performance. The simultaneous chaining paradigm delivered rewards only after subjects responded in the correct order to all stimuli displayed on a touch sensitive video monitor. The transitive inference paradigm presented pairs of items and delivered rewards when subjects selected the item with the lower ordinal rank. After learning a list in one paradigm, subjects’ knowledge of that list was tested using the other paradigm. Performance was enhanced from the very start of transfer training. Transitive inference performance was characterized by ‘symbolic distance effects,’ whereby the ordinal distance between stimuli in the implied list ordering was strongly predictive of the probability of a correct response. The patterns of error displayed by subjects in both tasks were best explained by a spatially coded representation of list items, regardless of which task was used to learn the list. Our analysis permits properties of this representation to be investigated without the confound of verbal reasoning.     

Single, brief exposure to a 50 Hz magnetic field does not affect the performance of an object recognition task in adult mice

A number of studies have shown that power frequency magnetic fields may affect spatial memory functions in rodents. An experiment was performed using a spontaneous object recognition task to investigate if nonspatial working memory was similarly affected. Memory changes in adult, male C57BL/6J mice were assessed by measuring the relative time within which the animals explored familiar or novel stimulus objects. Between initial testing and retesting, the animals were exposed for 45 min to a 50 Hz magnetic field at either 7.5 microT, 75 microT or 0.75 mT. Other animals were sham-exposed with ambient fields of less than 50 nT. No significant field-dependent effects on the performance of the task were observed at any flux density (for all measures, P > 0.05). These data provide no evidence to suggest that nonspatial working memory was affected in mice by acute exposure to an intense 50 Hz magnetic field.     

Human Left Ventral Premotor Cortex Mediates Matching of Hand Posture to Object Use

Visuomotor transformations for grasping have been associated with a fronto-parietal network in the monkey brain. The human homologue of the parietal monkey region (AIP) has been identified as the anterior part of the intraparietal sulcus (aIPS), whereas the putative human equivalent of the monkey frontal region (F5) is located in the ventral part of the premotor cortex (vPMC). Results from animal studies suggest that monkey F5 is involved in the selection of appropriate hand postures relative to the constraints of the task. In humans, the functional roles of aIPS and vPMC appear to be more complex and the relative contribution of each region to grasp selection remains uncertain. The present study aimed to identify modulation in brain areas sensitive to the difficulty level of tool object - hand posture matching. Seventeen healthy right handed participants underwent fMRI while observing pictures of familiar tool objects followed by pictures of hand postures. The task was to decide whether the hand posture matched the functional use of the previously shown object. Conditions were manipulated for level of difficulty. Compared to a picture matching control task, the tool object – hand posture matching conditions conjointly showed increased modulation in several left hemispheric regions of the superior and inferior parietal lobules (including aIPS), the middle occipital gyrus, and the inferior temporal gyrus. Comparison of hard versus easy conditions selectively modulated the left inferior frontal gyrus with peak activity located in its opercular part (Brodmann area (BA) 44). We suggest that in the human brain, vPMC/BA44 is involved in the matching of hand posture configurations in accordance with visual and functional demands.