Mixed Segregation and Recombination of Chromosomes and Yacs during Single-Division Meiosis in Spo13 Strains of Saccharomyces Cerevisiae |
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| Authors: | Y. Hugerat and G. Simchen |
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| Affiliation: | Department of Genetics, The Hebrew University of Jerusalem, Jerusalem 91904, Israel |
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| Abstract: | Diploid yeast strains, homozygous for the mutation spo13, undergo a single-division meiosis and form dyads (two spores held together in one ascus). Dyad analysis of spo13/spo13 strains with centromere-linked markers on five different chromosomes and on a pair of human DNA YACs shows that: (a) in spo13 meiosis, chromosomes undergo mixed segregation, namely some chromosomes segregate reductionally whereas others, in the same cell, segregate equationally; (b) different chromosomes exhibit different segregation tendencies; (c) recombination between homologous chromosomes might not determine that a bivalent undergoes reductional rather than equational segregation. |
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