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USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation
Authors:Jack Green  Ana Valera  Fatima Martín‐Sánchez  Carolina Pellegrini  David Brough  Gloria López‐Castejón
Affiliation:1. Division of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, School of Biological Sciences, University of Manchester, Manchester, UK;2. Departamento de Biología Celular e Histología, Facultad de Biología, Instituto Murciano de Investigación Biosanitaria (IMIB‐Arrixaca), Universidad de Murcia, Murcia, Spain;3. Grupo de Inflamación Molecular, Centro de Investigación Biomédica en Red en el área Temática de Enfermedades Hepáticas y Digestivas, Hospital Clínico Universitario Virgen de la Arrixaca (IMIB‐Arrixaca), Murcia, Spain;4. Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy;5. Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, Manchester Collaborative Centre of Inflammation Research, Manchester Academic Health Science Centre, Core Technology Facility, School of Biological Sciences, University of Manchester, Manchester, UK
Abstract:
Keywords:deubiquitination  inflammasome  macrophages  USP47  USP7
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