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Synthesis of a mammalian parvovirus in Brij-58-lysed cells.
Authors:M Gautschi and P Reinhard
Abstract:An in vitro system was developed, prepared by lysis of parvovirus LuIII-infected cells with Brij-58. In this subcellular system, DNA of viral genome size and synthesized and subsequently packaged into particles with physicochemical properties of mature LuIII virions.
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