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Complementation and Noncomplementation among Nonallelic Mutations Altering Development in SCHIZOPHYLLUM COMMUNE
Authors:Klein K K  Deppe C S
Affiliation:Department of Genetics and Cell Biology, University of Minnesota, St. Paul, Minnesota 55101, and Department of Biology, Hamline University, St. Paul, Minnesota 55104.
Abstract:Mutations resistant to compounds that alter the development of Schizophyllum commune (cyclic adenosine monophosphate, caffeine and imidazole) were selected. These mutations defined four genes, car (cAMP resistance), caf-1 and caf-2 (caffeine resistance) and imr (imidazole resistance). The mutations were found to be noncomplementing in certain pairs when tested against each other and against two previously isolated developmental mutations, B-con and sep (septateless), in fully compatible, forced heterokaryons. The pattern of complementation in fully compatible diploids showed noncomplementation only between allelic mutations, except for one case, imr vs. car.
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