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High fat diet‐induced oxidative stress blocks hepatocyte nuclear factor 4α and leads to hepatic steatosis in mice
Authors:Dongsheng Yu  Gang Chen  Minglin Pan  Jia Zhang  Wenping He  Yang Liu  Xue Nian  Liang Sheng  Bin Xu
Affiliation:1. Department of Pharmacology, School of Basic Medical Science, Nanjing Medical University, Nanjing, Jiangsu, China;2. Department of Hepatobiliary Surgery, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China;3. Department of Endocrinology, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China;4. Department of Gastroenterology and Hepatology, Zhongda Hospital, Nanjing, Jiangsu, China;5. Institute of Gastroenterology and Hepatology, School of Medicine, Southeast University, Nanjing, Jiangsu, China;6. Department of Internal Medicine, Division of Metabolism, Endocrinology and Diabetes, University of Michigan Medical Center, Ann Arbor, Michigan
Abstract:
Keywords:apolipoprotein B  HNF4α    NAFLD  oxidative stress  protein kinase C  VLDL secretion
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