Mutation Frequencies at Defined Single Codon Sites in Vesicular Stomatitis Virus and Poliovirus Can Be Increased Only Slightly by Chemical Mutagenesis |
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Authors: | John J. Holland Esteban Domingo Juan Carlos de la Torre David A. Steinhauer |
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Affiliation: | Institute of Molecular Genetics, University of California, San Diego, La Jolla 92093. |
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Abstract: | Mutagenesis by a variety of chemical mutagens conferred only 1.1- to 2.8-fold increases in mutation frequencies at defined single base sites in vesicular stomatitis virus and poliovirus. |
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