|
|||||
|
|
A comparison of the effects of prednisolone and methylprednisolone on human lymphoblastoid cells. |
|
| Authors: | A W Waddell and A R Currie |
| Abstract: | Methylprednisolone is more effective than prednisolone in mediating long-term cytolysis and immediate inhibition of nucleoside uptake in human lymphoblastoid cells. This suggests that methylation of prednisolone makes it more potent by aiding interaction with a cellular target rather than increasing its stability. |
| Keywords: | |