The Salmonella typhimurium uracil-sensitive mutation use is in argU and encodes a minor arginine tRNA. |
| |
| Authors: | C D Lu and A T Abdelal |
| |
| Abstract: | The use gene of Salmonella typhimurium was previously identified by a mutation conferring sensitivity to uracil in glucose minimal medium. The use gene was cloned and identified as an allele of argU encoding a tRNA for a minor arginine codon (CGG). The uracil-sensitive phenotype was shown to result from a base substitution in the anticodon stem of this tRNA. |
| |
| Keywords: | |
|
|
