Relationship between intracellular amino acids and protein synthesis in the extensor digitorum longus muscle of rats |
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Authors: | R. C. Hider E. B. Fern D. R. London |
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Affiliation: | Department of Chemical Pathology, St Thomas''s Hospital Medical School, London S.E.1 |
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Abstract: | 1. The incorporation into protein, and the accumulation into the free amino acid pools, of radioactive l-leucine and glycine was studied in rat extensor digitorum longus muscle. 2. The tissue was incubated first with (14)C-labelled and then with (3)H-labelled amino acid. 3. The experimental results were consistent with a model based on the premise that the amino acids in protein were incorporated directly from the extracellular pool. |
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