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Genetic characterization of an avian H4N6 influenza virus isolated from the Izumi plain,Japan
Authors:Masakazu Kuwahara  Aya Matsuu  Tatsunori Masatani  Shigehisa Toda  Makoto Ozawa
Affiliation:1. Matsuoka Research Institute for Science, Tokyo 184‐0003 , Japan;2. Transboundary Animal Diseases Research Center, Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan;3. United Graduate School of Veterinary Science, Yamaguchi University, Yamaguchi, Japan;4. Kagoshima Crane Conservation Committee, Izumi, Kagoshima 899‐0208, Japan;5. Joint Faculty of Veterinary Medicine, Laboratory of Animal Hygiene, Kagoshima University, Kagoshima, Japan
Abstract:
An influenza A virus of H4N6 subtype was isolated from the Izumi plain, Japan, in 2013. Genetic analyses revealed that two viral genes (M and NS gene segments) of this isolate were genetically distinct from those of the H4N6 virus isolated from the same place in 2012. Furthermore, three viral genes (PB2, PB1 and M gene segments) of this isolate share high similarity with those of the North American isolates of 2014. These results suggest a high frequency of genetic reassortment of avian influenza viruses in Asian waterfowl and intercontinental movements of avian influenza viruses via migratory waterfowl.
Keywords:avian influenza viruses  genetic reassortment  intercontinental movements  migratory waterfowl
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