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Proteomic analysis of host cell protein dynamics in the supernatant of Fc‐fusion protein‐producing CHO DG44 and DUKX‐B11 cell lines in batch and fed‐batch cultures
Authors:Jin Hyoung Park  Jong Hwa Jin  In Jung Ji  Hyun Joo An  Jong Won Kim  Gyun Min Lee
Affiliation:1. Department of Biological Sciences, KAIST, Daejeon 34141, Republic of Korea;2. New Drug Development Center, Cheongju‐si, Chungbuk, Republic of Korea;3. Graduate School of Analytical Science & Technology, Chungnam National University, Daejon, Republic of Korea;4. +82‐42‐350‐2618+82‐42‐350‐2610 0000-0002-9876-7378 Department of Biological Sciences, KAIST, Daejeon 34141, Republic of Korea
Abstract:
Keywords:host cell proteins  Chinese hamster ovary cells  proteomics  Fc‐fusion protein  product quality  fed‐batch culture
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