|
|||||
|
|
Generation of apoptosis‐resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production |
|
| Authors: | Weifeng Zhang Dan Xiao Linlin Shan Junli Zhao Qinwen Mao Haibin Xia |
| Affiliation: | 1. Department of Biochemistry, Laboratory of Gene Therapy, College of Life Sciences, Shaanxi Normal University, Xi'an, Shaanxi, P.R. China;2. Department of Burns and Cutaneous Surgery, Xijing Hospital, the Fourth Military Medical University, Xi'an, Shaanxi, China;3. Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois |
| Abstract: | |
| Keywords: | adenovirus apoptosis CRISPR/Cas gene therapy genome editing |