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Rapid Buffer and Ligand Screening for Affinity Chromatography by Multiplexed Surface Plasmon Resonance Imaging
Authors:Karin P. M. Geuijen  Daniëlle E. J. W. van Wijk‐Basten  David F. Egging  Richard B. M. Schasfoort  Michel H. Eppink
Affiliation:1. Downstream Processing, Synthon Biopharmaceuticals BV, Nijmegen, The Netherlands;2. Bioprocess Engineering, Wageningen University, Wageningen, The Netherlands;3. Preclinical Department, Synthon Biopharmaceuticals BV, Nijmegen, The Netherlands;4. Medical Cell Biophysics Group, MIRA institute, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands
Abstract:
Keywords:continuous flow micro elution screening  ligand selection  process miniaturization  protein A affinity chromatography  surface plasmon resonance
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