5-Aminolevulinate Synthesis in Permeabilized Filaments of the Blue-Green Alga Anabaena variabilis |
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| Authors: | Avissar Y J |
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| Affiliation: | Department of Applied Hydrobiology, Desert Research Institute, Ben Gurion University of the Negev, Beer Sheva, 84120, Israel. |
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| Abstract: | Filaments of the blue-green alga Anabaena variabilis permeabilized by dimethylsulfoxide (DMSO) produce increased amounts of 5-aminolevulinate in the presence of levulinic acid. The metabolic activity of the filaments remains unperturbed in the presence of up to 7.5% (v/v) DMSO. Studies utilizing DMSO-permeabilized filaments confirm that 5-aminolevulinate is synthesized preferably from glutamate and, to a lesser extent, from α-ketoglutarate in this organism. |
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