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DNA methylation aberrations rather than polymorphisms of FZD3 gene increase the risk of spina bifida in a high‐risk region for neural tube defects
Authors:Shaoyan Chang  Xiaoling Lu  Zhen Wang  Lihua Wu  Jianhua Wang  Xiuwei Wang  Zhen Guan  Yihua Bao  Huizhi Zhao  Jizhen Zou  Bo Niu  Ting Zhang
Affiliation:1. Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing, China;2. Department of Biotechnology, Capital Institute of Pediatrics, Beijing, China;3. Department of Pathology, Capital Institute of Pediatrics, Beijing, China
Abstract:
Keywords:spina bifida  FZD3 gene  DNA methylation  single nucleotide polymorphism  planar cell polarity
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