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Haemanthus coccineus extract and its main bioactive component narciclasine display profound anti‐inflammatory activities in vitro and in vivo
Authors:Simone Fuchs  Louise T. Hsieh  Werner Saarberg  Clemens A. J. Erdelmeier  Thomas A. Wichelhaus  Liliana Schaefer  Egon Koch  Robert Fürst
Affiliation:1. Institute of Pharmaceutical Biology, Biocenter, Goethe‐University, Frankfurt/Main, Germany;2. Department of Pharmacy, Pharmaceutical Biology, University of Munich, Munich, Germany;3. Institute of Pharmacology and Toxicology/ZAFES, Medical School, Goethe‐University, Frankfurt/Main, Germany;4. Preclinical Research, Dr. Willmar Schwabe GmbH & Co. KG, Karlsruhe, Germany;5. Institute of Medical Microbiology and Infection Control, Medical School, Goethe‐University, Frankfurt/Main, Germany
Abstract:
Keywords:adhesion molecules  endothelium  Haemanthus coccineus extract  inflammation  isocarbostyril alkaloid  narciclasine  leucocyte‐endothelial cell interactions  NFκ  B
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