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Telocytes and interstitial cells of Cajal in the biliary system
Authors:Lei Chen  Baoping Yu
Affiliation:1. Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan, China;2. Hubei Key Laboratory of Digestive System Disease, Wuhan, China
Abstract:A novel type of interstitial tissue cells in the biliary tree termed telocytes (TCs), formerly known as interstitial Cajal‐like cells (ICLCs), exhibits very particular features which unequivocally distinguish these cells from interstitial cells of Cajal (ICCs) and other interstitial cell types. Current research substantiates the existence of TCs and ICCs in the biliary system (gallbladder, extrahepatic bile duct, cystic duct, common bile duct and sphincter of Oddi). Here, we review the distribution, morphology and ultrastructure of TCs and ICCs in the biliary tree, with emphasis on their presumptive roles in physiological and pathophysiological processes.
Keywords:biliary system  extrahepatic bile ducts  gallbladder  interstitial cells of Cajal  telocytes
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