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Thyroid FNAC: Causes of false‐positive results
Authors:D. C. Malheiros  S. Canberk  D. N. Poller  F. Schmitt
Affiliation:1. Faculdade de Ciências, Médicas da Santa Casa de S?o Paulo, S?o Paulo, Brasil;2. IPATIMUP, Institute of Molecular Pathology and Immunology of University of Porto, Porto, Portugal;3. I3S, Instituto de Investiga??o e Inova??o em Saúde, University of Porto, Porto, Portugal;4. Department of Pathology subdivision of Cytopathology, Acibadem University, Atasehir‐Istanbul, Turkey;5. Department of Pathology, Queen Alexandra Hospital, Portsmouth, UK;6. Medical Faculty of Porto University, Porto, Portugal
Abstract:In this paper, we aim to focus on false positive results in the evaluation of thyroid aspirations, covering cystic, inflammatory, follicular and oncocytic lesions, papillary carcinoma, and medullary carcinoma of thyroid. The recently described entity noninvasive follicular thyroid neoplasm with papillary‐like nuclear features is also discussed detailing the impact of its introduction on the sensitivity and specificity of thyroid FNA, as well as the use of molecular tests for diagnostics. Medicolegal issues in relation to current practice in English law are also described.
Keywords:false‐positive  follicular‐pattern lesions  noninvasive follicular thyroid neoplasm with papillary‐like nuclear features  thyroid carcinoma  thyroid FNA
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