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Studies on the tissue specificity of the high-mobility-group non-histone chromosomal proteins from calf. |
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| Authors: | A Rabbani G H Goodwin E W Johns |
| Abstract: | The high-mobility-group (HMG) non-histone chromosomal proteins from calf thymus, liver, spleen and kidney were extracted, and fractionated by CM-Sephadex chromatography and trichloroacetic acid precipitation. The isolated proteins HMG 1, HMG 2 and HMG 17 from the tissues were compared by polyacrylamide-gel electrophoresis, isoelectric focusing and amino acid analysis. The results show that the three proteins are very similar in the tissues studied, implying a lack of tissue specificity. |
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