flaD (sinR) mutations affect SigD-dependent functions at multiple points in Bacillus subtilis. |
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| Authors: | M H Rashid and J Sekiguchi |
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| Abstract: | A flaD (sinR) null mutation depressed sigD-lacZ expression only two- to fourfold, whereas a flaD1 point mutation depressed it almost completely. Introduction of pHYSigD, a sigmaD-overproducing plasmid, corrected the filamentous phenotype common to both sinR mutants; autolysin synthesis was restored partially and completely in the flaD1 and flaD (sinR) null strains, respectively. Flagellin synthesis and motility were not restored at all in either strain. |
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