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Insight in schizophrenia spectrum disorders: relationship with behavior,mood and perceived quality of life,underlying causes and emerging treatments
Authors:Paul H. Lysaker  Michelle L. Pattison  Bethany L. Leonhardt  Scott Phelps  Jenifer L. Vohs
Affiliation:1. Roudebush VA Medical Center, Indiana University School of Medicine, Indianapolis, IN, USA;2. College of Applied Behavioral Sciences, University of Indianapolis, Indianapolis, IN, USA;3. Indiana University School of Medicine, Eskenazi Health‐Midtown Community Mental Health, Indianapolis, IN, USA;4. Wesleyan University, Middletown, CT, USA;5. Indiana University School of Medicine, Indianapolis, IN, USA
Abstract:Poor insight in schizophrenia is prevalent across cultures and phases of illness. In this review, we examine the recent research on the relationship of insight with behavior, mood and perceived quality of life, on its complex roots, and on the effects of existing and emerging treatments. This research indicates that poor insight predicts poorer treatment adherence and therapeutic alliance, higher symptom severity and more impaired community function, while good insight predicts a higher frequency of depression and demoralization, especially when coupled with stigma and social disadvantage. This research also suggests that poor insight may arise in response to biological, experiential, neuropsychological, social‐cognitive, metacognitive and socio‐political factors. Studies of the effects of existing and developing treatments indicate that they may influence insight. In the context of earlier research and historical models, these findings support an integrative model of poor insight. This model suggests that insight requires the integration of information about changes in internal states, external circumstances, others’ perspectives and life trajectory as well as the multifaceted consequences and causes of each of those changes. One implication is that treatments should, beyond providing education, seek to assist persons with schizophrenia to integrate the broad range of complex and potentially deeply painful experiences which are associated with mental illness into their own personally meaningful, coherent and adaptive picture.
Keywords:Insight  schizophrenia  treatment adherence  therapeutic alliance  antipsychotic medication  depression  quality of life  neurocognition  social cognition  metacognition  stigma  psychotherapy  recovery
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