Virion-Associated RNA Primer for Rous Sarcoma Virus DNA Synthesis: Isolation from Uninfected Cells |
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Authors: | Robert C. Sawyer Fumio Harada James E. Dahlberg |
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Affiliation: | Department of Physiological Chemistry, University of Wisconsin Medical School, Madison, Wisconsin 53706 |
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Abstract: | Uninfected chicken, duck, rat, and human fibroblast cells in culture contained a tRNA-like RNA molecule which was structurally identical to a virion-associated RNA primer for in vitro Rous sarcoma virus DNA synthesis. This primer RNA appeared to be a normal tRNA of these cells. It was not found in a number of lower eukaryotic cells or in Escherichia coli. |
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