Production of Luteoskyrin, a Hepatotoxic Pigment, by Penicillium islandicum Sopp |
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| Authors: | Yoshio Ueno and Ichijiro Ishikawa |
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| Abstract: | Various factors affecting the yields of luteoskyrin, a hepatotoxic mycotoxin, and related pigments in the liquid medium were studied. Maximal yields of luteoskyrin (0.13% by isolation) and of other pigments were attained in the late phase of the cultivation. The yield of the pigment was increased by supplying malt extract, malonic acid, glutamic acid, or asparagine. A useful material for preparation of (14)C-labeled luteoskyrin was 2-(14)C-malonate. |
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