An overview of the potassium channel family |
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| Authors: | Christopher Miller |
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| Affiliation: | (1) HHMI and Department of Biochemistry, Brandeis University, Waltham, MA 02454, USA |
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| Abstract: | Potassium channels, tetrameric integral membrane proteins that form aqueous pores through which K+ can flow, are found in virtually all organisms; the genomes of humans, Drosophila, and Caenorhabditis elegans contain 30-100 K+ channel genes each. The structure of a bacterial K+ channel, sequence comparisons with other channels and electrophysiological measurements have enabled conclusions about the mechanism of gating and ion flow to be drawn for many other channels. |
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