High Count Rates with Total Internal Reflection Fluorescence Correlation Spectroscopy |
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| Authors: | Kai Hassler Rudolf Rigler Theo Lasser |
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| Affiliation: | * Ecole Polytechnique Fédérale de Lausanne (EPFL), Laboratoire d’Optique Biomédicale, CH-1015 Lausanne, Switzerland
† Fraunhofer Institut für Biomedizinische Technik (IBMT), D-66386 St. Ingbert, Germany |
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| Abstract: | We achieved photon count rates per molecule as high as with commonly used confocal fluorescence correlation spectroscopy instruments using a new total internal reflection fluorescence correlation spectroscopy system based on an epi-illumination configuration. |
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