DNA binding of the mouse class II major histocompatibility CCAAT factor depends on two components. |
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| Authors: | A Celada and R A Maki |
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| Affiliation: | La Jolla Cancer Research Foundation, California 92037. |
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| Abstract: | A CCAAT-binding factor that recognizes a CCAAT sequence (Y box) located upstream of the major histocompatibility class II gene I-A beta has been partially purified. This CCAAT-binding factor was found to consist of two components, designated factors A and B, both of which were required for efficient binding to the DNA. Factor A had an apparent molecular size of 34 kilodaltons, and factor B had an apparent molecular size of 42 to 46 kilodaltons. |
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