Direct Determination of the Lamellar Structure of Peripheral Nerve Myelin at Moderate Resolution (7 Å) |
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| Authors: | C. R. Worthington and T. J. McIntosh |
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| Abstract: | Low-angle X-ray diffraction patterns have been recorded from normal nerve and nerve swollen in glycerol solutions. The new X-ray data have a resolution of 7 Å. Direct methods of structure analysis which include deconvolution of the auto-correlation function and sampling theorem reconstructions have been used in the interpretation of the X-ray data. Phases have been assigned to the first 12 orders of diffraction from normal nerve. Fourier syntheses at a resolution of 7 Å are described and an absolute electron density scale is derived. A possible molecular interpretation of the electron density profile is given. |
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