Establishment of cytotoxic T-cell clones specific for cells infected with mouse hepatitis virus. |
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| Authors: | K Yamaguchi S Kyuwa K Nakanaga M Hayami |
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| Affiliation: | Department of Animal Pathology, University of Tokyo, Japan. |
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| Abstract: | Mouse hepatitis virus (MHV)-specific T-lymphocyte clones were established from MHV-infected BALB/c mice. They expressed Thy1 and Lyt2 antigens but lacked L3T4 and NK1 antigens. The clones killed MHV-infected but not uninfected or influenza virus-infected J774.1 cells. The specificity was further defined by a cold-target competition test. |
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