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Computed tomography or necropsy diagnosis of multiple bullae and the treatment of pneumothorax in rhesus macaques (Macaca mulatta)
Authors:Jong‐Min Kim  Sungyoung Han  Jun‐Seop Shin  Byoung‐Hoon Min  Won Young Jeong  Ga Eul Lee  Min Sun Kim  Ju Eun Kim  Hyunwoo Chung  Chung‐Gyu Park
Affiliation:1. Xenotransplantation Research Center, Seoul National University Graduate School, Seoul, Korea;2. Institute of Endemic Diseases, Seoul National University Graduate School, Seoul, Korea;3. Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea;4. Seoul Animal Medical Center, Seoul, Korea;5. Department of Microbiology and Immunology, Seoul National University Graduate School, Seoul, Korea;6. Cancer Research Institute, Seoul National University Graduate School, Seoul, Korea;7. Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea
Abstract:Pulmonary bullae and pneumothorax have various etiologies in veterinary medicine. We diagnosed multiple pulmonary bullae combined with or without pneumothorax by computed tomography (CT) or necropsy in seven rhesus macaques (Macaca mulatta) imported from China. Two of seven rhesus macaques accompanied by pneumothorax were cured by fixation of ruptured lung through left or right 3rd intercostal thoracotomy. Pneumonyssus simicola, one of the etiologies of pulmonary bullae, was not detected from tracheobronchiolar lavage. To the best of our knowledge, this is the first case report on the CT‐aided diagnosis of pulmonary bullae and the successful treatment of combined pneumothorax by thoracotomy in non‐human primates (NHPs).
Keywords:Computed tomography  pneumothorax  pulmonary bullae  rhesus macaque
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