Inhibition of Cleavage of Large Poliovirus-Specific Precursor Proteins in Infected HeLa Cells by Inhibitors of Proteolytic Enzymes |
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| Authors: | Donald F. Summers Elliott N. Shaw Margaret L. Stewart Jacob V. Maizel Jr. |
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| Affiliation: | Departments of Cell Biology and Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461;Department of Biology, Brookhaven National Laboratory, Upton, Long Island, New York |
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| Abstract: | Inhibitors of chymotrypsin interfere with the post-translational cleavage of large poliovirus-specific polypeptides in the molecular weight range of 100,000 to 250,000 in infected HeLa cells. |
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