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Transformation of Folate-Consuming Lactobacillus gasseri into a Folate Producer
Authors:Arno Wegkamp   Marjo Starrenburg   Willem M. de Vos   Jeroen Hugenholtz     Wilbert Sybesma
Abstract:Five genes essential for folate biosynthesis in Lactococcus lactis were cloned on a broad-host-range lactococcal vector and were transferred to the folate auxotroph Lactobacillus gasseri. As a result L. gasseri changed from a folate consumer to a folate producer. This principle can be used to increase folate levels in many fermented food products.
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