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Accelerated uptake of 5-hydroxytryptamine by human blood platelets enriched in a sialic acid. |
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| Authors: | Szabados L Mester F Michal G V Born |
| Abstract: | The enzymically catalysed incorporation of N-acetylneuraminic acid into human platelets, whether suspended in their own citrated plasma or in buffered saline containing 0.17 mM-sucrose, accelerated the uptake of 5-hydroxytryptamine. This acceleration decreased with time. The observations may be explained by assuming that N-acetylneuraminic acid is a component of a transport receptor for 5-hydroxytryptamine. |
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