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Studies on flavonoid metabolism. Biosynthesis of (+)-[14C]catechin by the plant Uncaria gambir Roxb
Authors:N. P. Das and L. A. Griffiths
Affiliation:Department of Biochemistry, Faculty of Medicine, University of Singapore, Singapore 3;Department of Physiological Chemistry, University of Birmingham
Abstract:1. The formation of (+)-[14C]catechin has been demonstrated in Uncaria gambir after the administration of 14CO2 and [1-14C]acetate. 2. By alkaline degradation to phloroglucinol and protocatechuic acid it has been shown that administration of 14CO2 resulted in equal labelling of the A and B rings of catechin, whereas [1-14C]-acetate gave rise to labelling largely in the A ring. 3. Incorporation of 14C from both 14CO2 and [1-14C]acetate into (+)-catechin was greater in young than in older leaves.
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