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Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha‐galactosidase A (GLA) enzymes
Authors:Tiziana Squillaro  Ivana Antonucci  Nicola Alessio  Anna Esposito  Marilena Cipollaro  Mariarosa Anna Beatrice Melone  Gianfranco Peluso  Liborio Stuppia  Umberto Galderisi
Affiliation:1. Department of Experimental Medicine, Biotechnology and Molecular Biology Section, University of Campania “Luigi Vanvitelli”, Naples, Italy;2. Institute of Bioscience and Bioresources, National Research Council, Naples, Italy;3. Laboratory of Molecular Genetics, Department of Psychological, Health and Territorial Sciences, School of Medicine and Health Sciences, G. d'Annunzio University, Chieti‐Pescara, Italy;4. Department of Medical, Surgical, Neurological, Metabolic Sciences, and Aging;5. Division of Neurology and InterUniversity Center for Research in Neurosciences, University of Campania “Luigi Vanvitelli”, Naples, Italy
Abstract:
Keywords:autophagy  fabry disease  gaucher disease  lysosomal storage disorders  mesenchymal stem cells  senescence
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