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New Acetophenone Derivatives from Acronychia oligophlebia and Their Anti‐inflammatory and Antioxidant Activities
Authors:Yuan‐Lin Zhong  Qian‐Wen Niu  Ying‐Ying Li  Yu‐Bo Zhang  Man‐Mei Li  Yao‐Lan Li  Guo‐Cai Wang
Affiliation:1. Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou, P. R. China;2. Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research, Jinan University, Guangzhou, P. R. China
Abstract:Seven new acetophenone derivatives (acroliones A – G, 1  –  7 ) and three known ones ( 8  –  10 ) were isolated from the leaves of Acronychia oligophlebia. Their structures were elucidated based on extensive spectroscopic analyses (IR, UV, HR‐ESI‐MS, 1D‐ and 2D‐NMR), X‐ray diffraction and comparison with literature data. The anti‐inflammatory and antioxidant activities of all isolates were evaluated.
Keywords:   Acronychia oligophlebia     acetophenone derivatives  structural elucidation  anti‐inflammatory activity  antioxidant activity
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