Different evolutionary patterns between young duplicate genes in the human genome |
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| Authors: | Zhang Peng Gu Zhenglong Li Wen-Hsiung |
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| Affiliation: | (1) Department of Ecology and Evolution, University of Chicago, East 57th Street, 60637 Chicago, IL, USA; |
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| Abstract: | Background Following gene duplication, two duplicate genes may experience relaxed functional constraints or acquire different mutations, and may also diverge in function. Whether the two copies will evolve in different patterns remains unclear, however, because previous studies have reached conflicting conclusions. In order to resolve this issue, by providing a general picture, we studied 250 independent pairs of young duplicate genes from the whole human genome. |
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