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盐酸戊乙奎醚与丙泊酚联合用于无痛人工流产术的临床研究
引用本文:夏明,姚蓓,刘梦婷,童建华,刘杨,李伟彦. 盐酸戊乙奎醚与丙泊酚联合用于无痛人工流产术的临床研究[J]. 现代生物医学进展, 2012, 12(34): 6677-6680
作者姓名:夏明  姚蓓  刘梦婷  童建华  刘杨  李伟彦
作者单位:南京军区南京总医院麻醉科 江苏南京210002
基金项目:国家自然科学基金项目(30872424)
摘    要:目的:评价盐酸戊乙奎醚联合丙泊酚减轻人工流产术后疼痛的效果.方法:ASAⅠ-H级人工流产术患者100例,随机分为观察组和对照组.处理组先缓慢静脉注射盐酸戊乙奎醚注射剂1mg,30min后静脉注射丙泊酚2.5mg/kg;;对照组单独静脉注射丙泊酚2.5mg/kg.两组丙泊酚静注速率均为5mg/s.结果:处理组苏醒即刻苏醒后15min和30min宫缩痛的VAS评分分别为(3.13±0.15)、(2.02±0.11)和(0.87±0.09)分,明显低于对照组的(4.47± 0.35)、(3.54± 0.14)及(2.01±0.12)(P<0.01).结论:盐酸戊乙奎醚联合丙泊酚镇痛能减轻人工流产术后的疼痛.

关 键 词:盐酸戊乙奎醚  丙泊酚  人工流产术  术后疼痛

Effect of Penehyclidine Hydrochloride with Propofol Analgesia on the Postoperative Pain in Painless Artificial Abortion
XIA Ming,YAO Bei,LIU Meng-ting,TONG Jian-hua,LIU Yang,LI Wei-yan. Effect of Penehyclidine Hydrochloride with Propofol Analgesia on the Postoperative Pain in Painless Artificial Abortion[J]. Progress in Modern Biomedicine, 2012, 12(34): 6677-6680
Authors:XIA Ming  YAO Bei  LIU Meng-ting  TONG Jian-hua  LIU Yang  LI Wei-yan
Affiliation:(Department of Anesthesiology,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing,Jiangsu,210002,China)
Abstract:Objective: To evaluate the effect of Penehyclidine Hydrochloride with propofol analgesia on the postoperative pain in painless artificial abortion.Methods: One hundred ASA I-II patients undergoing artificial abortion were randomly assigned to two groups(n=50 each): control group(con) were was administrated propofol 2.5mg/kg alone.Treatment group was administrated intravenously Penehyclidine Hydrochloride 1mg followed by propofol 2.5mg/kg 30minutes later.The speed of intravenously injection of propofol was 5mg/s in two groups.Results: The VAS scores at immediate time of awaked from anesthesia,15min and 30min after that were(3.13± 0.15)、(2.02±0.11)and(0.87±0.09),respectively,in treatment group,which were significantly shorter than(4.47±0.35)、(2.02± 0.11)and(2.01±0.12)in control grouo(P0.01).Conclusion: Penehyclidine Hydrochloride combined with propofol anesthesia can effectively relieve the postoperative pain of artificial abortion.
Keywords:Penehyclidine Hydrochloride  Propofol  Artificial abortion
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