Characterization of the proteoglycogen fraction non-extractable from retina by trichloroacetic acid. |
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| Authors: | M C Miozzo E R Lacoste J A Curtino |
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| Affiliation: | Department de Quimica Biologica-CIQUIBIC, Facultad de Ciencias Quimicas-CONICET, Cordoba, Argentina. |
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| Abstract: | The trichloroacetic acid-insoluble 1,4-alpha-glucan fraction from bovine retina was purified and characterized. It is a proteoglycogen fraction containing a 42 kDa protein moiety similar in size to the protein moiety of the trichloroacetic acid-soluble proteoglycogen fraction. The apparent weight-average Mr of acid-insoluble and acid-soluble proteoglycogens are 4.7 x 10(5) and 7.0 x 10(5) respectively. The present results support suggestions from earlier studies indicating that acid-insoluble proteoglycogen is the precursor of the acid-soluble form. |
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