| 益生菌联合口腔洁治对慢性萎缩性胃炎的疗效及安全性评价 |
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| 引用本文： | 匡哲. 益生菌联合口腔洁治对慢性萎缩性胃炎的疗效及安全性评价[J]. 中国微生态学杂志, 2020, 32(6): 688-691. doi: 10.13381/j.cnki.cjm.202006015 |
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| 作者姓名： | 匡哲 |
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| 作者单位： | 北京市平谷区医院 消化科,北京 101200 |
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| 摘 要： | 目的 对益生菌联合口腔洁治治疗慢性萎缩性胃炎的有效性、安全性进行评价。 方法 选择2015年12月到2018年2月我院收治的102例慢性萎缩性胃炎患者为研究对象,随机分为对照组(n=51)与观察组(n=51)。对照组患者采用益生菌治疗,观察组在对照组基础上予以口腔洁治进行治疗。对两组患者治疗的有效性、安全性进行比较。 结果 观察组患者总有效率(92.16%)高于对照组(68.63%),差异有统计学意义(χ2=8.956,P=0.003)。治疗前,两组患者病理和症状评分差异无统计学意义(t=0.226、0.142,P=0.087、0.074)。治疗后,两组患者病理和症状评分均显著降低,且观察组患者病理评分(5.22±1.03)和症状评分(6.46±1.24)均低于对照组的病理评分(7.59±1.22)和症状评分(9.16±1.25),差异有统计学意义(t=10.600、10.951,P2=13.222,P2=9.871,P=0.001)。 结论 在慢性萎缩性胃炎治疗中应用益生菌联合口腔洁治具有显著效果,安全性较高,值得推广。
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| 关 键 词： | 慢性萎缩性胃炎 益生菌 口腔洁治 病状评分 不良反应 |
Efficacy and safety of probiotics combined with oral scaling for chronic atrophic gastritis |
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| KUANG Zhe. Efficacy and safety of probiotics combined with oral scaling for chronic atrophic gastritis[J]. Chinese Journal of Microecology, 2020, 32(6): 688-691. doi: 10.13381/j.cnki.cjm.202006015 |
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| Authors: | KUANG Zhe |
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| Affiliation: | Department of Gastroenterology, Pinggu District Hospital, Beijing 101200, China |
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| Abstract: | Objective To evaluate the efficacy and safety of probiotics combined with oral scaling for chronic atrophic gastritis. Methods A total of 102 patients with chronic atrophic gastritis treated in our hospital from December 2015 to February 2018 were randomly divided into control group (n=51) or observation group (n=51). The efficacy and safety in the two groups were compared. Results The total efficiency rate in the observation group was 92.16%, higher than the 68.63% in the control group, and the difference was statistically significant (χ2=8.956, P=0.003). Before treatment, there were no significant differences in pathological and symptom scores between the two groups (t=0.226,0.142; P=0.087,0.074). After treatment, the pathological and symptom scores in both groups were significantly lower. The pathological score and the symptom score in the observation group were 5.22±1.03 and 6.46±1.24, significantly lower than those in control group (7.59±1.22 and 9.16±1.25) respectively(t=10.600,10.951; P2=13.222, P2=9.871, P=0.001). Conclusion Probiotics combined with oral scaling in the treatment of chronic atrophic gastritis has significant effect and is safe. |
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| Keywords: | Chronic atrophic gastritis Probiotics Oral scaling Symptom score Adverse reactions |
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