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Quantitative Comparisons of 16S rRNA Gene Sequence Libraries from Environmental Samples |
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| Authors: | David R. Singleton Michelle A. Furlong Stephen L. Rathbun William B. Whitman |
| Abstract: | To determine the significance of differences between clonal libraries of environmental rRNA gene sequences, differences between homologous coverage curves, CX(D), and heterologous coverage curves, CXY(D), were calculated by a Cramér-von Mises-type statistic and compared by a Monte Carlo test procedure. This method successfully distinguished rRNA gene sequence libraries from soil and bioreactors and correctly failed to find differences between libraries of the same composition. |
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