饥饿胁迫对小鼠学习记忆、SOD和心肌丙二醛的影响

给小鼠断绝食物，观察小鼠学习记忆能力的变化及生理应激反应。结果表明，饥饿后小鼠的体重明显减轻，学习能力明显增强，记忆能力和大脑5－羟色胺含量无明显改变，心肌丙二醛含量下降，肝组织超氧化物歧化酶（SOD）活性无明显改变，血浆SOD活性提高，血浆SOD同工酶变带无明显改变。提示饥饿胁迫使小鼠产生适应性的生理反应，使小鼠学习能力提高，加强延缓机体衰退的生理功能；这些应激反应有利于小鼠在逆境下的生存。

Effects of Hunger Stress on Learning, Memory, SOD and Myocardium Malondialdehyde in Mice

Changes in mouse learning ability and memory, as well as emergency physiological reactions, were observed during hunger stress. During starvation, mouse body weight significantly decreased, learning ability and superoxide dismutase plasma activity increased and the content of myocardium malondialdehyde became significantly reduced. There were no significant changes in memory ability, the 5 hydroxytryptamine level of cerebrum, the SOD activity of liver and the number of SOD isozymes in the plasma of starved mice. These results indicate that hunger stress could cause mice to procreate as an adaptive physiological reaction, increase learning ability and delay senescence. These emergency reactions to starvation are beneficial to the survival of mice in adverse environmental conditions.