口服补钙对甘肃鼢鼠钙磷代谢的影响

利用原子吸收分光光度计、可见光分光光度计、全自动生化分析仪测定了2007年4～5月捕获的甘肃鼢鼠(Myospalax cansus)补钙组(n=7)和对照组(n=7)股骨钙、磷含量,血浆钙、磷浓度,分析口服补钙对甘肃鼢鼠钙、磷代谢的影响,初步探讨甘肃鼢鼠钙、磷吸收机制。结果表明,甘肃鼢鼠补钙后股骨钙、磷含量明显增加(P0.05),血浆钙、磷浓度无明显变化(P0.05),股骨钙、磷含量与钙、磷摄入总量显著正相关(P0.01),呈不饱和趋势,股骨钙、磷含量与血浆钙、磷浓度呈不显著负相关(P0.05)。说明甘肃鼢鼠骨骼对钙、磷有较高储留能力,推测甘肃鼢鼠对钙、磷的吸收可能是非依赖VD3的被动吸收途径。

Effect of Oral Calcium Intake on Ca /P Metabolism in Gansu Zokor

The effect of calcium supplement in diet on the metabolism of Ca and P in Gansu Zokor (Myospalax cansus) was determined by comparison of calcium supplement group(n =7) and control group (n =7) during April to May,2007. The contents of Ca and P in femur and plasma of Gansu Zokor were detected respectively by AAS (Atomic Absorption Spectrometry),SP (Spectrophotometry),and by Auto Biochemistry Analyzer. The results showed that the contents of femur Ca and P increased significantly (P < 0.05) after Ca supplementation in diet,and that significantly positive correlation between Ca /P absorption and the contents of femur Ca /P(P < 0.01)was found. However,the concentrations of plasma Ca and P did not change (P > 0.05),and there was negative correlation,although not significant (P > 0.05),between the concentration of plasma Ca /P and the contents of femur Ca /P after treatment. It is suggested that high efficiency of Ca /P retention in Gansu Zokor may rely on a VD₃ independent passive pathway.