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X射线对仔鼠皮肤组织结构及c-Fos、KGF表达的影响
引用本文:王悦,邓海平,俞诗源.X射线对仔鼠皮肤组织结构及c-Fos、KGF表达的影响[J].动物学杂志,2011,46(3):123-130.
作者姓名:王悦  邓海平  俞诗源
作者单位:西北师范大学生命科学学院;
基金项目:国家自然科学基金项目(No.30370163); 甘肃省创新人才基金项目
摘    要:应用生物显微技术和免疫组织化学方法,研究了不同剂量X射线(0.0、3.5、6.5 Gy)辐射对发育期(1、5、10和20 d)昆明小鼠(Mus musculus)仔鼠皮肤组织结构和c-Fos、KGF表达的影响,探讨了c-Fos、KGF的生物活性作用及调控意义,并利用IPP专业图像分析软件对其表达强度进行定量分析.结果表...

关 键 词:X射线  仔鼠  皮肤  组织结构  c-Fos  KGF
收稿时间:2010/10/15 0:00:00
修稿时间:2011/3/17 0:00:00

Effect of X-ray on Histological Structure as well as c-Fos and KGF Expression in Developing Mouse Skin
WANG Yue,DENG Hai-Ping and YU Shi-Yuan.Effect of X-ray on Histological Structure as well as c-Fos and KGF Expression in Developing Mouse Skin[J].Chinese Journal of Zoology,2011,46(3):123-130.
Authors:WANG Yue  DENG Hai-Ping and YU Shi-Yuan
Institution:WANG Yue DENG Hai-Ping YU Shi-Yuan College of Life Science,Northwest Normal University,Lanzhou 730070,China
Abstract:The effect of different dosages(0.0,3.5,6.5 Gy) of X-ray on histological structure and expression of c-Fos and KGF in skin of developing Mouse(Mus musculus)(1 d,5 d,10 d,20 d) were investigated.Results showed that skin structure was not obviously changed after 1 d irradiation;thickness of epidermis,dermis,hypodermis and number of hair decreased,and serious fibrosis appeared in skin of developing Mouse after 5 d irradiation;fibrosis reduced,dermis dense connective tissue and hypodermis recovered gradually af...
Keywords:X-ray  Develoing Mouse  Skin  Histological structure  C-Fos  KGF  
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