Structure of the O-polysaccharide from the lipopolysaccharide from Vibrio cholerae O6 |
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Authors: | Bergström Niklas Nair G Balakrish Weintraub Andrej Jansson Per-Erik |
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Institution: | Analytical Unit, Clinical Research Centre, Karolinska Institute, Huddinge University Hospital, Novum, SE-141 86, Sweden. |
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Abstract: | The O-polysaccharide from Vibrio cholerae O6 was isolated from the LPS by mild-acid hydrolysis and has been investigated by sugar and methylation analysis and NMR spectroscopy. The polysaccharide was also depolymerized with aqueous hydrofluoric acid to give the repeating unit and multiples thereof. The O-polysaccharide had the following tetrasaccharide repeating unit. Two O-acetyl groups are present, one of them making the GlcNAc residue fully substituted and the steric crowding considerable at the branching residue. |
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Keywords: | Lipopolysaccharide O-Antigen Bacterial polysaccharide Vibrio cholerae diarrhea |
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